Depends. If your dog has health issues now, you may see a dramatic change within a couple of weeks, but it depends on several factors - what the problem is, how long your dog has had it, what sort of treatment you have been doing up to this point, etc. If you read the comments some of our clients have sent in at, you'll read about some who have seen results in days. But on average, you should see noticeable results within one month.